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City of innovation

San Antonio company bags spot on Fortune's 2025 list of most innovative

H-E-B logo sign corporate campus downtown san antonio arsenal
H-E-B was the lone San Antonio company to make the prestigious list. Photo courtesy of H-E-B

A beloved San Antonio company has been named to Fortune’s third annual list of America’s Most Innovative Companies, joining another 24 from the state of Texas. Local grocery giant H-E-B ranks No. 201.

The group of 300 companies nationwide was rated based on production innovation, process innovation, and innovation culture, according to Fortune. In partnership with Statista, the magazine considered IP portfolios, employee, expert and customer opinions; and many other factors.

While many of the top-rated companies fell into the tech sector, Fortune reports that health care companies made up the largest portion of the 2025 list. Sixty-three honorees fell into the health care category.

Dallas-Fort Worth claimed the largest number of Texas companies on the list. Houston was home to the second-most with eight hailing from the Bayou City. Austin is home to only four of the companies on the list, however, companies from the Capital City ranked higher on average, with Oracle, Tesla and Dell Technologies claiming the top three spots for the state. H-E-B was the one company to represent San Antonio.

Here's how all the Texas companies fared:

  • No. 6 — Oracle
  • No. 11 — Tesla
  • No. 14 — Dell Technologies
  • No. 35 — Houston Methodist
  • No. 37 — AT&T
  • No. 52 — SpaceX
  • No. 54 — ExxonMobil
  • No. 59 — Texas Instruments
  • No. 89 — Charles Schwab
  • No. 91 — McKesson
  • No. 113 — Jacobs Solutions
  • No. 125 — Baylor Scott & White Health
  • No. 137 — NRG Energy
  • No. 158 — Hewlett-Packard Enterprise
  • No. 165 — Frontier Communications
  • No. 169 — BMC Software
  • No. 175 — Texas Children’s Hospital
  • No. 201— H-E-B
  • No. 210 — CBRE Group
  • No. 219 — TTEC Holdings
  • No. 223 — GameStop
  • No. 227 — Sysco
  • No. 251 — American Airlines Group
  • No. 268 — Chevron
  • No. 271 — Caterpillar

California-based tech conglomerate Alphabet Inc. topped the list for the third year in a row, and California companies again represented the majority of companies on the list, according to Fortune. Alphabet, Microsoft, Apple, IBM and Salesforce made up the top five, of which three are headquartered in California.

The 2025 group had a median revenue of $22 billion over the last 12 months, according to Fortune. See the full report here.

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This story originally appeared on our sister site, InnovationMap.

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